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 Osteopontin and Angiogenesis

M. Zhu et al., Osteopontin sequence modified mesoporous calcium silicate scaffolds to promote angiogenesis in bone tissue regeneration. J Mater Chem B 8, 5849 (2020). https://www.ncbi.nlm.nih.gov/pubmed/32530014

Y. Li et al., ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis. Biol Chem,  (2020). https://www.ncbi.nlm.nih.gov/pubmed/32845856

M. Wein et al., Differential osteopontin expression in human osteoblasts derived from iliac crest and alveolar bone and its role in early stages of angiogenesis. J Bone Miner Metab 37, 105 (2019).https://www.ncbi.nlm.nih.gov/pubmed/29327303

A. Mirzaei et al., Osteopontin b and c Splice isoforms in Leukemias and Solid Tumors: Angiogenesis Alongside Chemoresistance. Asian Pac J Cancer Prev 19, 615 (2018). https://www.ncbi.nlm.nih.gov/pubmed/29580029

X. X. Yao et al., Hairy/enhancer of Split Homologue-1 Suppresses Vascular Endothelial Growth Factor-induced Angiogenesis via Downregulation of Osteopontin Expression. Sci Rep 7, 898 (2017). https://www.ncbi.nlm.nih.gov/pubmed/28420872

E. Babarovic et al., The expression of osteopontin and vascular endothelial growth factor in correlation with angiogenesis in monoclonal gammopathy of undetermined significance and multiple myeloma. Pathol Res Pract 212, 509 (2016). https://www.ncbi.nlm.nih.gov/pubmed/26997492

F. Wehrhan et al., BRONJ-related jaw bone is associated with increased Dlx-5 and suppressed osteopontin-implication in the site-specific alteration of angiogenesis and bone turnover by bisphosphonates. Clin Oral Investig 19, 1289 (2015). https://www.ncbi.nlm.nih.gov/pubmed/25467232

Y. Lin et al., Inorganic phosphate induces cancer cell mediated angiogenesis dependent on forkhead box protein C2 (FOXC2) regulated osteopontin expression. Mol Carcinog 54, 926 (2015). https://www.ncbi.nlm.nih.gov/pubmed/24700685

S. Kale et al., Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via alpha9beta1 integrin. Oncogene 34, 5408 (2015). https://www.ncbi.nlm.nih.gov/pubmed/26473949

X. L. Wu et al., Osteopontin knockdown suppresses the growth and angiogenesis of colon cancer cells. World J Gastroenterol 20, 10440 (2014). https://www.ncbi.nlm.nih.gov/pubmed/25132760

R. Raja et al., Hypoxia-driven osteopontin contributes to breast tumor growth through modulation of HIF1alpha-mediated VEGF-dependent angiogenesis. Oncogene 33, 2053 (2014). https://www.ncbi.nlm.nih.gov/pubmed/23728336

S. Kale et al., Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via alpha9beta1 integrin. Oncogene 33, 2295 (2014). https://www.ncbi.nlm.nih.gov/pubmed/23728342

A. Gupta, C. Q. Zhou, M. A. Chellaiah, Osteopontin and MMP9: Associations with VEGF Expression/Secretion and Angiogenesis in PC3 Prostate Cancer Cells. Cancers (Basel) 5, 617 (2013). https://www.ncbi.nlm.nih.gov/pubmed/24216994

A. M. Abu El-Asrar et al., Osteopontin and other regulators of angiogenesis and fibrogenesis in the vitreous from patients with proliferative vitreoretinal disorders. Mediators Inflamm 2012, 493043 (2012). https://www.ncbi.nlm.nih.gov/pubmed/23055574

Y. Wang et al., Overexpression of osteopontin induces angiogenesis of endothelial progenitor cells via the avbeta3/PI3K/AKT/eNOS/NO signaling pathway in glioma cells. Eur J Cell Biol 90, 642 (2011). https://www.ncbi.nlm.nih.gov/pubmed/21616556

H. L. Wang, L. H. Ruan, X. Q. Zhao, [Expression of osteopontin and VEGF in acute leukemia and their relationship with angiogenesis]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 19, 926 (2011). https://www.ncbi.nlm.nih.gov/pubmed/21867616

A. Sfiridaki et al., Circulating osteopontin: a dual marker of bone destruction and angiogenesis in patients with multiple myeloma. J Hematol Oncol 4, 22 (2011). https://www.ncbi.nlm.nih.gov/pubmed/21548993

X. L. Du et al., Inhibition of osteopontin suppresses in vitro and in vivo angiogenesis in endometrial cancer. Gynecol Oncol 115, 371 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19783287

J. Dai et al., Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells. Oncogene 28, 3412 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19597469

K. Matusan-Ilijas et al., Osteopontin expression correlates with angiogenesis and survival in malignant astrocytoma. Pathol Oncol Res 14, 293 (2008). https://www.ncbi.nlm.nih.gov/pubmed/18493866

G. Chakraborty, S. Jain, G. C. Kundu, Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms. Cancer Res 68, 152 (2008). https://www.ncbi.nlm.nih.gov/pubmed/18172307

G. Chakraborty et al., Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin-induced VEGF expression. Mol Med Rep 1, 641 (2008). https://www.ncbi.nlm.nih.gov/pubmed/21479462

H. Tang et al., Inhibition of osteopontin would suppress angiogenesis in gastric cancer. Biochem Cell Biol 85, 103 (2007). https://www.ncbi.nlm.nih.gov/pubmed/17464350

Y. Tanaka et al., Myeloma cell-osteoclast interaction enhances angiogenesis together with bone resorption: a role for vascular endothelial cell growth factor and osteopontin. Clin Cancer Res 13, 816 (2007). https://www.ncbi.nlm.nih.gov/pubmed/17289872

C. L. Duvall et al., Impaired angiogenesis, early callus formation, and late stage remodeling in fracture healing of osteopontin-deficient mice. J Bone Miner Res 22, 286 (2007). https://www.ncbi.nlm.nih.gov/pubmed/17087627

S. Jain, G. Chakraborty, G. C. Kundu, The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis. Cancer Res 66, 6638 (2006). https://www.ncbi.nlm.nih.gov/pubmed/16818637

G. Chakraborty et al., The multifaceted roles of osteopontin in cell signaling, tumor progression and angiogenesis. Curr Mol Med 6, 819 (2006). https://www.ncbi.nlm.nih.gov/pubmed/17168734

R. G. Seipelt et al., Osteopontin expression and adventitial angiogenesis induced by local vascular endothelial growth factor 165 reduces experimental aortic calcification. J Thorac Cardiovasc Surg 129, 773 (2005). https://www.ncbi.nlm.nih.gov/pubmed/15821643

S. Colla et al., Human myeloma cells express the bone regulating gene Runx2/Cbfa1 and produce osteopontin that is involved in angiogenesis in multiple myeloma patients. Leukemia 19, 2166 (2005). https://www.ncbi.nlm.nih.gov/pubmed/16208410

V. Cheriyath, M. A. Hussein, Osteopontin, angiogenesis and multiple myeloma. Leukemia 19, 2203 (2005). https://www.ncbi.nlm.nih.gov/pubmed/16208409

Y. Hamada et al., Osteopontin-derived peptide SVVYGLR induces angiogenesis in vivo. Dent Mater J 23, 650 (2004). https://www.ncbi.nlm.nih.gov/pubmed/15688734

M. Gattorno et al., Synovial expression of osteopontin correlates with angiogenesis in juvenile idiopathic arthritis. Rheumatology (Oxford) 43, 1091 (2004). https://www.ncbi.nlm.nih.gov/pubmed/15199218

D. Leali et al., Osteopontin (Eta-1) and fibroblast growth factor-2 cross-talk in angiogenesis. J Immunol 171, 1085 (2003). https://www.ncbi.nlm.nih.gov/pubmed/12847283

F. Takahashi et al., Osteopontin induces angiogenesis of murine neuroblastoma cells in mice. Int J Cancer 98, 707 (2002). https://www.ncbi.nlm.nih.gov/pubmed/11920639

M. Noda et al., [A gene involved in angiogenesis and bone -osteopontin]. Clin Calcium 12, 363 (2002). https://www.ncbi.nlm.nih.gov/pubmed/15775315

Y. Asou et al., Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone. Endocrinology 142, 1325 (2001). https://www.ncbi.nlm.nih.gov/pubmed/11181551

F. Prols, B. Loser, M. Marx, Differential expression of osteopontin, PC4, and CEC5, a novel mRNA species, during in vitro angiogenesis. Exp Cell Res 239, 1 (1998). https://www.ncbi.nlm.nih.gov/pubmed/9511718