Home      What does osteopontin do?      Immunity

Osteopontin and Immunity

R. Jiang, B. Lonnerdal, Effects of Milk Osteopontin on Intestine, Neurodevelopment, and Immunity. Nestle Nutr Inst Workshop Ser 94, 152 (2020). https://www.ncbi.nlm.nih.gov/pubmed/32172244

S. Scutera et al., Adaptive Regulation of Osteopontin Production by Dendritic Cells Through the Bidirectional Interaction With Mesenchymal Stromal Cells. Front Immunol 9, 1207 (2018). https://www.ncbi.nlm.nih.gov/pubmed/29910810

K. Zhao et al., Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response. Sci Rep 6, 23771 (2016). https://www.ncbi.nlm.nih.gov/pubmed/27026194

S. Mohammadi et al., Acquired expression of osteopontin selectively promotes enrichment of leukemia stem cells through AKT/mTOR/PTEN/beta-catenin pathways in AML cells. Life Sci 152, 190 (2016). https://www.ncbi.nlm.nih.gov/pubmed/27063991

A. Gela et al., Osteopontin That Is Elevated in the Airways during COPD Impairs the Antibacterial Activity of Common Innate Antibiotics. PLoS One 11, e0146192 (2016). https://www.ncbi.nlm.nih.gov/pubmed/26731746

N. Clemente et al., Osteopontin Bridging Innate and Adaptive Immunity in Autoimmune Diseases. J Immunol Res 2016, 7675437 (2016). https://www.ncbi.nlm.nih.gov/pubmed/28097158

J. H. Chang et al., Utility of Plasma Osteopontin Levels in Management of Community-Acquired Pneumonia. Int J Med Sci13, 673 (2016). https://www.ncbi.nlm.nih.gov/pubmed/27647996

E. K. Kim et al., Tumor-derived osteopontin suppresses antitumor immunity by promoting extramedullary myelopoiesis. Cancer Res 74, 6705 (2014). https://www.ncbi.nlm.nih.gov/pubmed/25273090

J. L. Chan, T. M. Reeves, L. L. Phillips, Osteopontin expression in acute immune response mediates hippocampal synaptogenesis and adaptive outcome following cortical brain injury. Exp Neurol 261, 757 (2014). https://www.ncbi.nlm.nih.gov/pubmed/25151457

A. Brown, Osteopontin: A Key Link between Immunity, Inflammation and the Central Nervous System. Transl Neurosci 3, 288 (2012). https://www.ncbi.nlm.nih.gov/pubmed/23565338

M. Inoue, M. L. Shinohara, Intracellular osteopontin (iOPN) and immunity. Immunol Res 49, 160 (2011). https://www.ncbi.nlm.nih.gov/pubmed/21136203

M. Inoue et al., Cutting edge: critical role of intracellular osteopontin in antifungal innate immune responses. J Immunol186, 19 (2011). https://www.ncbi.nlm.nih.gov/pubmed/21135164

G. J. van der Windt et al., Osteopontin is not crucial to protective immunity during murine tuberculosis. Immunology128, e766 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19740338

Y. Maeno et al., Effect of osteopontin on diarrhea duration and innate immunity in suckling mice infected with a murine rotavirus. Viral Immunol 22, 139 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19327001

T. Gu et al., Osteopontin is involved in the development of acquired chemo-resistance of cisplatin in small cell lung cancer. Lung Cancer 66, 176 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19285749

K. Alain et al., Osteopontin: an early innate immune marker of Escherichia coli mastitis harbors genetic polymorphisms with possible links with resistance to mastitis. BMC Genomics 10, 444 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19765294

Y. Maeno et al., Osteopontin is involved in Th1-mediated immunity against Plasmodium falciparum infection in a holoendemic malaria region in Vietnam. Acta Trop 98, 305 (2006). https://www.ncbi.nlm.nih.gov/pubmed/16765311

B. Abel et al., Osteopontin is not required for the development of Th1 responses and viral immunity. J Immunol 175, 6006 (2005). https://www.ncbi.nlm.nih.gov/pubmed/16237095

A. W. O'Regan et al., Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks. Immunol Today 21, 475 (2000). https://www.ncbi.nlm.nih.gov/pubmed/11071524

S. Ashkar et al., Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science 287, 860 (2000). https://www.ncbi.nlm.nih.gov/pubmed/10657301