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Osteopontin and Wound Healing 

Z. Feldbrin et al., Osteopontin levels in plasma, muscles, and bone in patient with non-healing diabetic foot ulcers: A new player in wound healing process? J Diabetes Complications 32, 795 (2018). https://www.ncbi.nlm.nih.gov/pubmed/29871782

W. Wang et al., Osteopontin activates mesenchymal stem cells to repair skin wound. PLoS One 12, e0185346 (2017). https://www.ncbi.nlm.nih.gov/pubmed/28957406

J. Wu, Z. Wang, Osteopontin improves adhesion and migration of human primary renal cortical epithelial cells during wound healing. Oncol Lett 12, 4556 (2016). https://www.ncbi.nlm.nih.gov/pubmed/28101213

S. Saika et al., Wakayama symposium: modulation of wound healing response in the corneal stroma by osteopontin and tenascin-C. Ocul Surf 11, 12 (2013). https://www.ncbi.nlm.nih.gov/pubmed/23321354

A. O'Loughlin et al., Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model. Stem Cell Res Ther 4, 158 (2013). https://www.ncbi.nlm.nih.gov/pubmed/24444259

C. E. Weber et al., Epithelial-mesenchymal transition, TGF-beta, and osteopontin in wound healing and tissue remodeling after injury. J Burn Care Res 33, 311 (2012). https://www.ncbi.nlm.nih.gov/pubmed/22561306

M. D. McKee, C. E. Pedraza, M. T. Kaartinen, Osteopontin and wound healing in bone. Cells Tissues Organs 194, 313 (2011). https://www.ncbi.nlm.nih.gov/pubmed/21576907

C. E. Pedraza et al., Osteopontin functions as an opsonin and facilitates phagocytosis by macrophages of hydroxyapatite-coated microspheres: implications for bone wound healing. Bone 43, 708 (2008). https://www.ncbi.nlm.nih.gov/pubmed/18656563

R. Mori, T. J. Shaw, P. Martin, Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring. J Exp Med 205, 43 (2008). https://www.ncbi.nlm.nih.gov/pubmed/18180311

K. Miyazaki et al., Corneal wound healing in an osteopontin-deficient mouse. Invest Ophthalmol Vis Sci 49, 1367 (2008). https://www.ncbi.nlm.nih.gov/pubmed/18385052

L. Liaw et al., Altered wound healing in mice lacking a functional osteopontin gene (spp1). J Clin Invest 101, 1468 (1998). https://www.ncbi.nlm.nih.gov/pubmed/9525990

M. D. McKee, A. Nanci, Secretion of Osteopontin by macrophages and its accumulation at tissue surfaces during wound healing in mineralized tissues: a potential requirement for macrophage adhesion and phagocytosis. Anat Rec 245, 394 (1996). https://www.ncbi.nlm.nih.gov/pubmed/8769675